Falak Shah have completed his education in Bachelor of Dental Surgery (B.D.S) from AMC Dental College & Hospital, Ahmedabad, India which is affiliated with Gujarat University. At the moment studying Health Systems Management in Ontario, Canada.
This review aims to determine the use of saliva in the diagnosis of various oral disease. As the types of oral disease present across various parts of the country is not homogeneous. There is the prevalence of a large amount of disparity too. It is said that “healthy mouth & healthy body go hand in hand”. The proportion of oral disease frequency is said to be 5 and 20 percent of populations which accounts to be a sixth most common condition. Various methods can be engaged in the process of diagnosis of oral diseases like Sjogren's syndrome, Oral lichen planus (OLP), Oral Cancer, Salivary Gland Tumor etc. are: SalivaBio Children’s Swab (SCS), Oral fluid nanosensor test (OFNASET). SalivaBio Oral Swab (SOS), Parotid saliva (PR) collection. However, the methods which can be used for diagnosis are, ELISA (enzyme-linked immunosorbent assay), Twodimensional electrophoresis (2DE), Matrix-assisted laser desorption/ ionization time-of-flight mass spectrometry (MALDI-TOF-MS) and Western blot (WB) test. As a result the unstimulated and stimulated whole saliva from patients having oral disease was significantly decreased compared with controls. However, the TNF-alpha levels also increase with greater pace in patients having oral lichen planus when it is compared to a healthy individual. The poster will demonstrate that salivary fluid can be ideally used for the detection of pro-inflammatory markers of the oral cavity. It can also be used to measure the level of TNF-alpha in OLP patient’s saliva, cytokines, CgA, and SIgA in case of xerostomia which will ultimately useful in diagnosis for Sjogren's syndrome, glycoprotein M2BP for oral cancer