Kanwaldeep Singh Soodan
Maharishi Markandeshwar University, India
Title: Study of effect of polyvinylpyrrolidone-iodine (PVP-I) 2% as an anti-oedematous agent in third molar surgery
Biography
Biography: Kanwaldeep Singh Soodan
Abstract
A single-blind randomized control trial was carried out on 50 healthy outpatients who required surgical removal of
mandibular third molars under local anesthesia were selected. The patients were divided into 2 groups (n=25), the
treatment (PVP-I) and control group (normal saline). The treatment group patients were irrigated using PVP-I 2% (w/v)
(Betadine, Win- Medicare, India) during bone guttering and tooth sectioning. The control group patients were irrigated with
saline (sodium chloride 0.9%, w/v; Parenteral Drugs, India) only. Procedures that exceeded more than 1 hour were excluded
from the study. Using Pederson difficulty index, patients with moderately difficulty index were chosen. All parameters for
swelling were recorded preoperatively, on the first, second and seventh postoperative days for both procedures. The data were
statistically analyzed using SPSS (version 22.0) software. Independent t-test was applied for an operative time in minutes and
the two groups matched (p>0.05) for operative time. For change in swelling, T-tests was applied and we found an increase in
swelling in the saline group which was highly significant for change from preoperative to day 2 (p=0.005) and from preoperative
to day 7 (p-value<0.001). Mean for Pederson index for betadine and saline group was found out to be same (P=1). PVP-I 2%
was found out to be significantly reducing swelling as compared to saline suggesting that it acts as an anti-oedematous agent in
mandibular third molar surgery.